- WEB EXCLUSIVE
- PE COFFEEHAUS
EPA has previously released a work plan, referred to as EDSP21, that described EPA’s plan to develop and validate new tools to screen and assess pesticides for EDSP purposes. These tools include computational toxicology methods and high-throughput screens to more quickly and cost-effectively assess potential chemical toxicity while minimizing the use of conventional whole animal studies.
The Comprehensive Management Plan also provides the following EDSP milestones and the fiscal years in which these activities will take place:
|Fiscal Year||EDSP Activity||Period of Activity|
|2013||Develop Data Evaluation Record Composers (.xml) for all Tier 1 assays and Data Management Capture Tools||2013-2014|
|2013||Tier 2 Inter-laboratory Validation External Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) Scientific Advisory Panel (SAP) Peer Review and development of standard evaluation procedures||2013-2014|
|2013||FIFRA SAP External Peer Review of Re-evaluation of Tier 1 battery and weight of evidence determinations (several FIFRA SAPs)||2013-2014|
|2013||Issuance of List 2 Substances, Tier 1 test orders and review of Other Scientifically Relevant Information||2013-2016|
|2014||Completion of List 1 Substances, Tier 1 assay scientific data reviews, data evaluation records (DER) and weight of evidence decisions||2014|
|2014||Issuance of List 1 Substances, Tier 2 test orders and review of Other Scientifically Relevant Information||2014-2015|
|2015||Data Review List 2 Substances, Tier 1 assay scientific data reviews, DERs and weight of evidence decisions||2015-2018|
|2016||Completion of List 1 Substances, Tier 2 assay scientific data reviews, DERs||2016-2018|
Of particular interest, EPA states that it will be reviewing the Tier 1 assay results from the chemicals that received EDSP Tier 1 orders (List 1 Substances) and submitting a subset of chemicals for the functionality of each assay and the battery as a whole to the FIFRA SAP in FY 2013. EPA also states that in addition to the review of Tier 1 data and completion of regulatory determinations for whether additional testing is warranted, the agency also plans in FY 2013 to issue the final second list of chemicals for Tier 1 screening (List 2 Substances) with additional test orders for the second list of chemicals to be issued incrementally over a three-year period.
EPA’s Comprehensive Management Plan also details: (1) the various cross-office workgroups and major committees that will be implementing the majority of the EDSP work; (2) the information technology infrastructure goals to develop a single, administrative system to issue and manage/track test orders, as well as receive and review studies and data, and to track regulatory progress/status, and a single, scientific system/database to store and analyze study results; and (3) EPA's annual planning, budgeting, and spending process for EDSP activities.