MoreBecause there are growing concerns over the impact of other chemicals in our waters that were not previously a worry, the EPA has been looking for alternative analytical methods.
On Aug. 21, 2012, the National Toxicology Program (NTP) Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) announced that it has received responses to the Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM).
The responses were regarding test method recommendations on the usefulness and limitations of the LUMICELL® ER (BG1Luc ER TA) test method to identify human estrogen receptor (ER) agaonist and antagonist activity of chemicals.
According to the notice, the responses are favorable and, as a result, the EPA intends to accept data from a new, alternative estrogen receptor binding test rather than only results from a test that is part of EPA's Endocrine Disruptor Screening Program (EDSP).
According to NTP, concurrence letters from EPA and other federal agencies have paved the way for this new, alternative test method. Information about the BG1Luc assay, including federal agencies’ responses, is available at this link.
EPA information about tests for its endocrine disruptor-screening program is available by clicking on this link.
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