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Draft Dioxin Report for Peer Review and Public Comment

May 24, 2010

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The EPA on Monday, May 24, 2010, announced it has reached a significant milestone toward the completion of the agency's dioxin reassessment with the public release of its draft scientific report, EPA's Reanalysis of Key Issues Related to Dioxin Toxicity and Response to NAS Comments.

The draft dioxin report includes an oral reference dose (RfD) for TCDD -- the most well-studied and considered to be among the most toxic of the dioxin-like compounds. An RfD was not in the 2003 draft dioxin reassessment.

The draft report is the agency's response to key comments and recommendations made by the National Academy of Sciences on the agency's draft dioxin reassessment. The EPA said it is moving forward with Administrator Lisa P. Jackson's commitment to complete the long-awaited dioxin reassessment. The draft report will now undergo scientific peer review by independent, external experts, as well as public review and comment.

The agency previously asked the National Academy of Sciences (NAS) to review EPA's 2003 draft dioxin reassessment. The NAS completed its review in 2006. The draft report released Monday contains the agency's response to key comments and recommendations in the NAS's 2006 report. The agency's draft report also includes significant new analyses that relate to issues raised by the NAS, including potential cancer and non-cancer human health effects that may result from exposures to dioxins.

The EPA and other federal agencies have updated a series of questions and answers to provide the public with general information on dioxins, including what they are, where they can be found, and major sources of dioxins. They also discuss possible effects of dioxin exposure in humans, include advice about consumption of food that might contain dioxins, and explain the review process for the dioxin reassessment. To view the questions and answers visit www.fda.gov/Food/FoodSafety/FoodContaminantsAdulteration/ChemicalContaminants/DioxinsPCBs/ucm077524.htm.

The draft report is available at www.epa.gov/dioxin. The Federal Register Notice, with details on the public comment process is at www.gpo.gov/fdsys/pkg/FR-2010-05-21/html/2010-12280.htm.

SOURCE: Federal Register 5/23/2010


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